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Karen Stokes

very nice Robert. Why is the ETO having opposite effects on the WT and KO in final fig?

Robert Schilke

Dr. Stokes, the loss of lipin-1 results in an increase in glycolysis and a shift to lipid synthesis. We believe that lipin-1 deficient macrophages are using incoming lipid for lipid synthetic events thus processing the lipid in another way. The WT macrophages have not switched their metabolism to compensate yet.

Shripa Amatya

Does the type of fat (saturated vs unsaturated) affect the process of efferocytosis in macrophages?